Evolution in organisms occurs through changes in heritable traits – particular characteristics of an organism. In humans, for example, eye color is an inherited characteristic and an individual might inherit the "brown-eye trait" from one of their parents.[29] Inherited traits are controlled by genes and the complete set of genes within an organism's genome is called its genotype.[30]
The complete set of observable traits that make up the structure and behavior of an organism is called its phenotype. These traits come from the interaction of its genotype with the environment.[31] As a result, many aspects of an organism's phenotype are not inherited. For example, suntanned skin comes from the interaction between a person's genotype and sunlight; thus, suntans are not passed on to people's children. However, some people tan more easily than others, due to differences in their genotype; a striking example are people with the inherited trait of albinism, who do not tan at all and are very sensitive to sunburn.[32]
Heritable traits are passed from one generation to the next via DNA, a molecule that encodes genetic information.[30] DNA is a long polymer composed of four types of bases. The sequence of bases along a particular DNA molecule specify the genetic information, in a manner similar to a sequence of letters spelling out a sentence. Before a cell divides, the DNA is copied, so that each of the resulting two cells will inherit the DNA sequence.
Portions of a DNA molecule that specify a single functional unit are called genes; different genes have different sequences of bases. Within cells, the long strands of DNA form condensed structures called chromosomes. The specific location of a DNA sequence within a chromosome is known as a locus. If the DNA sequence at a locus varies between individuals, the different forms of this sequence are called alleles. DNA sequences can change through mutations, producing new alleles. If a mutation occurs within a gene, the new allele may affect the trait that the gene controls, altering the phenotype of the organism.
However, while this simple correspondence between an allele and a trait works in some cases, most traits are more complex and are controlled by multiple interacting genes.[33][34] The study of such complex traits is a major area of current genetic research. Another unsolved question in genetics under active research asks whether or not epigenetics is important in evolution; that is, whether certain heritable traits, aspects of the environmental context of genome, are implicated in the evolution of organisms without there being any necessary change in the gene sequence.
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